Polythiazide

Chemical compound
  • C03AA05 (WHO)
Identifiers
  • 6-chloro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS Number
  • 346-18-9 checkY
PubChem CID
  • 4870
IUPHAR/BPS
  • 7274
ChemSpider
  • 4704 ☒N
UNII
  • 36780APV5N
KEGG
  • D00657 ☒N
ChEMBL
  • ChEMBL1587 ☒N
CompTox Dashboard (EPA)
  • DTXSID6025939 Edit this at Wikidata
ECHA InfoCard100.005.881 Edit this at WikidataChemical and physical dataFormulaC11H13ClF3N3O4S3Molar mass439.87 g·mol−1 ☒NcheckY (what is this?)  (verify)

Polythiazide is a thiazide diuretic.[1][2]

References

  1. ^ O'Brien ET, MacKinnon J (October 1972). "Propranolol and polythiazide in treatment of hypertension". British Heart Journal. 34 (10): 1042–4. doi:10.1136/hrt.34.10.1042. PMC 458544. PMID 5086971.
  2. ^ Monroy A, Plata C, Hebert SC, Gamba G (July 2000). "Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction". American Journal of Physiology. Renal Physiology. 279 (1): F161-9. doi:10.1152/ajprenal.2000.279.1.f161. PMID 10894798.
  • v
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Symporter inhibitors
Na+-Cl−
Na+-K+-Cl−
See also: Receptor/signaling modulators
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Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)
Vasopressin receptor inhibitors
(DCT and CD)
Other
Combination products
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