Azosemide

Chemical compound
  • none
Identifiers
  • 2-chloro-5-(2H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide
CAS Number
  • 27589-33-9 ☒N
PubChem CID
  • 2273
DrugBank
  • DB08961 ☒N
ChemSpider
  • 2186 checkY
UNII
  • MR40VT1L8Z
KEGG
  • D01323 checkY
ChEBI
  • CHEBI:31248 checkY
ChEMBL
  • ChEMBL1097235 checkY
CompTox Dashboard (EPA)
  • DTXSID7046910 Edit this at Wikidata
ECHA InfoCard100.044.121 Edit this at WikidataChemical and physical dataFormulaC12H11ClN6O2S2Molar mass370.83 g·mol−13D model (JSmol)
  • Interactive image
  • O=S(=O)(N)c2c(Cl)cc(c(c1n[nH]nn1)c2)NCc3sccc3
InChI
  • InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19) checkY
  • Key:HMEDEBAJARCKCT-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim.[1][2] As of 2015 it was available as a generic in some Asian countries.[3]


Azosemide has been found as an adulterant in ketamine.[4]

References

  1. ^ Sittig M (1988). Pharmaceutical Manufacturing Encyclopedia (PDF). Vol. 1. Noyes Publications. p. 122. ISBN 978-0-8155-1144-1. Archived from the original (PDF) on 2007-10-23.
  2. ^ Bormann D (January 1980). "Diuretics". In Hess HJ (ed.). Annual Reports in Medicinal Chemistry. Vol. 15. Academic Press. pp. 100–105 (101). ISBN 978-0-08-058359-4.
  3. ^ "International listings for azosemide". Drugs.com. Retrieved 23 July 2015.
  4. ^ "Drug Checking Report 2011" (PDF). Energy Control. Retrieved 20 January 2022.
  • v
  • t
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Diuretics (C03)
Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)Vasopressin receptor inhibitors
(DCT and CD)OtherCombination products
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