CDP-diacilglicerol—serin O-fosfatidiltransferaza
| CDP-diacilglicerol—serin O-fosfatidiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.8.8 | ||||||||
| CAS broj | 9068-48-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
CDP-diacilglicerol—serin O-fosfatidiltransferaza (EC 2.7.8.8, fosfatidilserinska sintaza, CDPdiglicerid-serinska O-fosfatidiltransferaza, PS sintaza, citidin 5'-difosfo-1,2-diacil-sn-glicerol (CDPdiglicerid):L-serin O-fosfatidiltransferaza, fosfatidilserin sintetaza, CDP-diacilglicerol-L-serin O-fosfatidiltransferaza, citidin difosfoglicerid-serin O-fosfatidiltransferaza, CDP-diglicerid-L-serin fosfatidiltransferaza, CDP-diglicerid:serin fosfatidiltransferaza, citidin 5'-difosfo-1,2-diacil-sn-glicerol:L-serin O-fosfatidiltransferaza, CDP-diacilglicerol:L-serin 3-O-fosfatidiltransferaza) je enzim sa sistematskim imenom CDP-diacilglicerol:L-serin 3-sn-fosfatidiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CDP-diacilglicerol + L-serin CMP + (3-sn-fosfatidil)-L-serin
Reference
- ↑ Larson, T.J. and Dowhan, W. (1976). „Ribosomal-associated phosphatidylserine synthetase from Escherichia coli: purification by substrate-specific elution from phosphocellulose using cytidine 5′-diphospho-1,2-diacyl-sn-glycerol”. Biochemistry 15: 5212-5218. PMID 187212.
- ↑ Raetz, C.R.H. and Kennedy, E.P. (1974). „Partial purification and properties of phosphatidylserine synthetase from Escherichia coli”. J. Biol. Chem. 249: 5038-5045. PMID 4604873.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH CDP-diacylglycerol---serine+O-phosphatidyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
