Phosphomevalonic acid

Phosphomevalonic acid
Names
IUPAC name
3-hydroxy-3-methyl- 5-phosphonooxy-pentanoic acid
Identifiers
CAS Number
  • 1189-94-2 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 463 ☒N
MeSH Phosphomevalonic+acid
PubChem CID
  • 476
CompTox Dashboard (EPA)
  • DTXSID00868263 Edit this at Wikidata
InChI
  • InChI=1S/C6H13O7P/c1-6(9,4-5(7)8)2-3-13-14(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H2,10,11,12) ☒N
    Key: OKZYCXHTTZZYSK-UHFFFAOYSA-N ☒N
  • CC(CCOP(=O)(O)O)(CC(=O)O)O
Properties
Chemical formula
 C6H13O7P
Molar mass 228.137 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound

Phosphomevalonic acid is an intermediate in the Mevalonate pathway.[1]

Mevalonate pathway. (Phosphomevalonic acid labeled as "mevalonate-5-phosphate"

References

  1. ^ Miziorko, Henry M. (2011-01-15). "Enzymes of the mevalonate pathway of isoprenoid biosynthesis". Archives of Biochemistry and Biophysics. 505 (2): 131–143. doi:10.1016/j.abb.2010.09.028. ISSN 0003-9861. PMC 3026612. PMID 20932952.
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Cholesterol and steroid metabolic intermediates
Mevalonate pathway
to HMG-CoA
Ketone bodies
to DMAPP
Geranyl-
Carotenoid
Non-mevalonate pathway
To CholesterolFrom Cholesterol
to Steroid hormones
  • 22R-Hydroxycholesterol
  • 20α,22R-Dihydroxycholesterol
  • See here instead.
Nonhuman
To Sitosterol
To Ergocalciferol


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