Estradiol propoxyphenylpropionate

Chemical compound
Estradiol propoxyphenylpropionate
Clinical data
Trade namesDurovex
Other namesEPPP; Estradiol 17-(4-propoxyphenyl)propanoate; Estradiol p-propoxyhydrocinnamate
Routes of
administration
Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
  • [(8R,9S,13S,14S,17S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-(4-propoxyphenyl)propanoate
CAS Number
  • 7724-88-1
PubChem CID
  • 90479312
ChemSpider
  • 34995669
UNII
  • 288OER048N
Chemical and physical data
FormulaC30H38O4
Molar mass462.630 g·mol−1
3D model (JSmol)
  • Interactive image
  • CCCOc1ccc(CCC(=O)O[C@H]2CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@]23C)cc1
InChI
  • InChI=1S/C30H38O4/c1-3-18-33-23-9-4-20(5-10-23)6-15-29(32)34-28-14-13-27-26-11-7-21-19-22(31)8-12-24(21)25(26)16-17-30(27,28)2/h4-5,8-10,12,19,25-28,31H,3,6-7,11,13-18H2,1-2H3/t25-,26-,27+,28+,30+/m1/s1
  • Key:JNWIUSBBFNMZRQ-BOJCFLQHSA-N

Estradiol propoxyphenylpropionate (EPPP), sold under the brand name Durovex, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β propoxyphenylpropionate (propoxyhydrocinnamate) ester of estradiol.[1] It is a long-acting depot estrogen.[2][3]

See also

References

  1. ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
  2. ^ Baker AP, Bergman F, Paul KG (April 1967). "Studies of eosinophil granulocytes. 3. Steroid hormones and number of eosinophils in the uterus of the mouse and rat". Acta Endocrinologica. 54 (4): 696–706. doi:10.1530/acta.0.0560221. PMID 6071489.
  3. ^ Åkeson Å, Ehrenberg A (17 May 2014). Structure and Function of Oxidation–Reduction Enzymes: Proceedings of the Wenner-Gren Symposium Held at the Wenner-Gren Center, Stockholm, 23–27 August, 1970. Elsevier. pp. 216–. ISBN 978-1-4831-4755-0.
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Estradiol
TopicsEsters
Related
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Estrogens and antiestrogens
Estrogens
ERTooltip Estrogen receptor agonists
Progonadotropins
Antiestrogens
ERTooltip Estrogen receptor antagonists
(incl. SERMsTooltip selective estrogen receptor modulators/SERDsTooltip selective estrogen receptor downregulators)
Aromatase inhibitors
Antigonadotropins
Others
See also
Estrogen receptor modulators
Androgens and antiandrogens
Progestogens and antiprogestogens
List of estrogens
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ERTooltip Estrogen receptor
Agonists
Mixed
(SERMsTooltip Selective estrogen receptor modulators)
Antagonists
  • Coregulator-binding modulators: ERX-11
GPERTooltip G protein-coupled estrogen receptor
Agonists
Antagonists
Unknown
See also
Receptor/signaling modulators
Estrogens and antiestrogens
Androgen receptor modulators
Progesterone receptor modulators
List of estrogens
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