Doxibetasol

Synthetic glucocorticoid corticosteroid
Doxibetasol
Clinical data
Other namesDoxybetasol; Deoxydexamethasone; 21-Deoxydexamethasone; GR 2/443; 9α-Fluoro-11β,17α-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,16S,17R)-17-Acetyl-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS Number
  • 1879-77-2
PubChem CID
  • 71106
UNII
  • 0JS043FG0D
ECHA InfoCard100.015.942 Edit this at Wikidata
Chemical and physical data
FormulaC22H29FO4
Molar mass376.468 g·mol−1
3D model (JSmol)
  • Interactive image
  • C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)C)O)C)O)F)C
InChI
  • InChI=1S/C22H29FO4/c1-12-9-17-16-6-5-14-10-15(25)7-8-19(14,3)21(16,23)18(26)11-20(17,4)22(12,27)13(2)24/h7-8,10,12,16-18,26-27H,5-6,9,11H2,1-4H3/t12-,16-,17-,18-,19-,20-,21-,22-/m0/s1
  • Key:IKGBPSZWCRRUQS-DTAAKRQUSA-N

Doxibetasol (doxybetasol; developmental code name GR 2/443) is a synthetic glucocorticoid corticosteroid.[1]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 470–. ISBN 978-1-4757-2085-3.


  • v
  • t
  • e
Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


Stub icon

This article about a steroid is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e