Α-Methylhistamine
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IUPAC name 1-(3H-Imidazol-4-yl)propan-2-amine | |
Systematic IUPAC name 1-(1H-Imidazol-4-yl)propan-2-amine[1] | |
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ChEBI |
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MeSH | Alpha-methylhistamine |
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InChI
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Properties | |
Chemical formula | C6H11N3 |
Molar mass | 125.175 g·mol−1 |
log P | -0.346 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
α-Methylhistamine is a histamine agonist selective for the receptor subtype H3. It causes lowering of blood pressure and a decrease of heart rate in animal models.[2]
References
- ^ "Chemical Entities of Biological Interest (ChEBI)".
- ^ McLeod, RL; Gertner, SB; Hey, JA (1993). "Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs". Br J Pharmacol. 110 (2): 553–558. doi:10.1111/j.1476-5381.1993.tb13846.x. PMC 2175947. PMID 7902173.
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Histamine receptor modulators
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- See also
- Receptor/signaling modulators
- Monoamine metabolism modulators
- Monoamine reuptake inhibitors
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